Yilmaz, B. & Li, H. Gut microbiota and iron: the crucial actors in health and disease. Pharmaceuticals (2018).
Seyoum, Y., Baye, K. & Humblot, C. Iron homeostasis in host and gut bacteria—a complex interrelationship. Gut Microbes 13, 1–19 (2021).
Google Scholar
Harbort, C. J. et al. Root-secreted coumarins and the microbiota interact to improve iron nutrition in Arabidopsis. Cell Host Microbe 28, 825–837 (2020).
Google Scholar
Stringlis, I. A. et al. MYB72-dependent coumarin exudation shapes root microbiome assembly to promote plant health. Proc. Natl Acad. Sci. USA 115, E5213–E5222 (2018).
Google Scholar
Ganz, T. & Nemeth, E. Iron homeostasis in host defence and inflammation. Nat. Rev. Immunol. 15, 500–510 (2015).
Google Scholar
Robinson, N. J., Procter, C. M., Connolly, E. L. & Guerinot, M. L. A ferric-chelate reductase for iron uptake from soils. Nature 397, 694–697 (1999).
Google Scholar
Eide, D., Broderius, M., Fett, J. & Guerinot, M. L. A novel iron-regulated metal transporter from plants identified by functional expression in yeast. Proc. Natl Acad. Sci. USA 93, 5624–5628 (1996).
Google Scholar
Vert, G. G. et al. IRT1, an Arabidopsis transporter essential for iron uptake from the soil and for plant growth. Plant Cell 14, 1223–1233 (2002).
Google Scholar
Schmidt, W., Michalke, W. & Schikora, A. Proton pumping by tomato roots. Effect of Fe deficiency and hormones on the activity and distribution of plasma membrane H+-ATPase in rhizodermal cells. Plant Cell Environ. 26, 361–370 (2003).
Google Scholar
Hentze, M. W., Muckenthaler, M. U., Galy, B. & Camaschella, C. Two to tango: regulation of mammalian iron metabolism. Cell 142, 24–38 (2010).
Google Scholar
Brown, J. C. Iron chlorosis in plants. Adv. Agron. 13, 329–369 (1961).
Google Scholar
Romera, F. J. et al. Induced systemic resistance (ISR) and Fe deficiency responses in dicot plants. Front. Plant Sci. 10, 287 (2019).
Google Scholar
Zamioudis, C. et al. Rhizobacterial volatiles and photosynthesis-related signals coordinate MYB72 expression in Arabidopsis roots during onset of induced systemic resistance and iron-deficiency responses. Plant J. 84, 309–322 (2015).
Google Scholar
Aznar, A., Patrit, O., Berger, A. & Dellagi, A. Alterations of iron distribution in Arabidopsis tissues infected by Dickeya dadantii. Mol. Plant Pathol. 16, 521–528 (2015).
Google Scholar
Xing, Y. et al. Bacterial effector targeting of a plant iron sensor facilitates iron acquisition and pathogen colonization. Plant Cell 33, 2015–2031 (2021).
Google Scholar
Nobori, T. et al. Transcriptome landscape of a bacterial pathogen under plant immunity. Proc. Natl Acad. Sci. USA 115, E3055–E3064 (2018).
Google Scholar
Gu, S. et al. Competition for iron drives phytopathogen control by natural rhizosphere microbiomes. Nat. Microbiol. 5, 1002–1010 (2020).
Google Scholar
Meziane, H., I, V. D. S., LC, V. A. N. L., Höfte, M. & Bakker, P. A. Determinants of Pseudomonas putida WCS358 involved in inducing systemic resistance in plants. Mol. Plant Pathol. 6, 177–185 (2005).
Google Scholar
Verbon, E. H. et al. Iron and immunity. Ann. Rev. Phytopathol. 55, 355–375 (2017).
Google Scholar
Platre, M. P. et al. The receptor kinase SRF3 coordinates iron-level and flagellin dependent defense and growth responses in plants. Nat. Commun. 13, 4445 (2022).
Google Scholar
Colangelo, E. P. & Guerinot, M. L. The essential basic helix-loop-helix protein FIT1 is required for the iron deficiency response. Plant Cell 16, 3400–3412 (2004).
Google Scholar
Grillet, L., Lan, P., Li, W., Mokkapati, G. & Schmidt, W. IRON MAN is a ubiquitous family of peptides that control iron transport in plants. Nat. Plants 4, 953–963 (2018).
Google Scholar
Kroh, G. E. & Pilon, M. Connecting the negatives and positives of plant iron homeostasis. N. Phytol. 223, 1052–1055 (2019).
Google Scholar
Ngou, B. P. M., Ahn, H.-K., Ding, P. & Jones, J. D. G. Mutual potentiation of plant immunity by cell-surface and intracellular receptors. Nature 592, 110–115 (2021).
Google Scholar
Yuan, M. et al. Pattern-recognition receptors are required for NLR-mediated plant immunity. Nature 592, 105–109 (2021).
Google Scholar
Dubeaux, G., Neveu, J., Zelazny, E. & Vert, G. Metal sensing by the IRT1 transporter-receptor orchestrates its own degradation and plant metal nutrition. Mol. Cell 69, 953–964 (2018).
Google Scholar
Martín-Barranco, A., Spielmann, J., Dubeaux, G., Vert, G. & Zelazny, E. Dynamic control of the high-affinity iron uptake complex in root epidermal cells. Plant Physiol. 184, 1236–1250 (2020).
Google Scholar
Faulkner, C. et al. LYM2-dependent chitin perception limits molecular flux via plasmodesmata. Proc. Natl Acad. Sci. USA 110, 9166–9170 (2013).
Google Scholar
Vatén, A. et al. Callose biosynthesis regulates symplastic trafficking during root development. Dev. Cell 21, 1144–1155 (2011).
Google Scholar
Li, Y. et al. IRON MAN interacts with BRUTUS to maintain iron homeostasis in Arabidopsis. Proc. Natl Acad. Sci. USA 118, e2109063118 (2021).
Google Scholar
Rodríguez-Celma, J. et al. Arabidopsis BRUTUS-LIKE E3 ligases negatively regulate iron uptake by targeting transcription factor FIT for recycling. Proc. Natl Acad. Sci. USA 116, 17584–17591 (2019).
Google Scholar
Liu, L. et al. Extracellular pH sensing by plant cell-surface peptide-receptor complexes. Cell 185, 3341–3355 (2022).
Google Scholar
Yu, K. et al. Rhizosphere-associated pseudomonas suppress local root immune responses by gluconic acid-mediated lowering of environmental pH. Curr. Biol. 29, 3913–3920 (2019).
Google Scholar
Liu, Y. et al. Plant commensal type VII secretion system causes iron leakage from roots to promote colonization. Nat. Microbiol. (2023).
Verbon, E. H. et al. Rhizobacteria-mediated activation of the Fe deficiency response in arabidopsis roots: impact on Fe status and signaling. Front. Plant Sci. (2019).
Zhou, F. et al. Co-incidence of damage and microbial patterns controls localized immune responses in roots. Cell 180, 440–453 (2020).
Google Scholar
Sanchez, K. K. et al. Cooperative metabolic adaptations in the host can favor asymptomatic infection and select for attenuated virulence in an enteric pathogen. Cell 175, 146–158 (2018).
Google Scholar
Hiruma, K. et al. Root endophyte colletotrichum tofieldiae confers plant fitness benefits that are phosphate status dependent. Cell 165, 464–474 (2016).
Google Scholar
Castrillo, G. et al. Root microbiota drive direct integration of phosphate stress and immunity. Nature 543, 513–518 (2017).
Google Scholar
Dindas, J. et al. Direct inhibition of phosphate transport by immune signaling in Arabidopsis. Curr. Biol. 32, 488–495 (2022).
Google Scholar
Gruber, B. D., Giehl, R. F. H., Friedel, S. & von Wirén, N. Plasticity of the Arabidopsis root system under nutrient deficiencies. Plant Physiol. 163, 161–179 (2013).
Google Scholar
Wyrsch, I., Domínguez-Ferreras, A., Geldner, N. & Boller, T. Tissue-specific FLAGELLIN-SENSING 2 (FLS2) expression in roots restores immune responses in Arabidopsis fls2 mutants. N. Phytol. 206, 774–784 (2015).
Google Scholar
Cao, M. et al. TMK1-mediated auxin signalling regulates differential growth of the apical hook. Nature 568, 240–243 (2019).
Google Scholar
Gautam, C. K., Tsai, H.-H. & Schmidt, W. A quick method to quantify iron in Arabidopsis seedlings. Bio Protoc. 12, e4342 (2022).
Google Scholar
Bayle, V., Platre, M. P. & Jaillais, Y. Automatic quantification of the number of intracellular compartments in Arabidopsis thaliana root cells. Bio Protoc. (2017).
Santi, S. & Schmidt, W. Dissecting iron deficiency-induced proton extrusion in Arabidopsis roots. N. Phytol. 183, 1072–1084 (2009).
Google Scholar
Gujas, B., Alonso-Blanco, C. & Hardtke, C. S. Natural Arabidopsis brx loss-of-function alleles confer root adaptation to acidic soil. Curr. Biol. 22, 1962–1968 (2012).
Google Scholar
Berardini, T. Z. et al. The Arabidopsis information resource: making and mining the “gold standard” annotated reference plant genome. Genesis 53, 474–485 (2015).
Google Scholar
Dobin, A. et al. STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29, 15–21 (2012).
Google Scholar
Robinson, M. D., McCarthy, D. J. & Smyth, G. K. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26, 139–140 (2010).
Google Scholar
Gu, Z., Eils, R. & Schlesner, M. Complex heatmaps reveal patterns and correlations in multidimensional genomic data. Bioinformatics 32, 2847–2849 (2016).
Google Scholar
:no_upscale()/cdn.vox-cdn.com/uploads/chorus_image/image/73043051/1915312386.0.jpg){kind=small}
