Scientists discovered a way to break apart the membranes of cancer cells by stimulating aminocyanine molecules with near-infrared light. Slashdot reader Baron_Yam shares a report from ScienceAlert: The research team from Rice University, Texas A&M University, and the University of Texas, says the new approach is a marked improvement over another kind of cancer-killing molecular machine previously developed, called Feringa-type motors, which could also break the structures of problematic cells. “It is a whole new generation of molecular machines that we call molecular jackhammers,” says chemist James Tour from Rice University. “They are more than one million times faster in their mechanical motion than the former Feringa-type motors, and they can be activated with near-infrared light rather than visible light.”
In tests on cultured, lab-grown cancer cells, the molecular jackhammer method scored a 99 percent hit rate at destroying the cells. The approach was also tested on mice with melanoma tumors, and half the animals became cancer-free. The structure and chemical properties of aminocyanine molecules mean they stay in sync with the right stimulus — such as near-infrared light. When in motion, the electrons inside the molecules form what’s known as plasmons, collectively vibrating entities that drive movement across the whole of the molecule. The plasmons have an arm on one side, helping to connect the molecules to the cancer cell membranes while the movements of the vibrations bash them apart. It’s still early days for the research, but these initial findings are very promising. The research has been published in Nature Chemistry.
